PDF's inside a Browser
Many PDF documents like manuals come with an Index document containing links to other PDF documents. If you have a web page that displays such a PDF document and would like to open those containing PDF links using adobe inside the browser, just make sure the following setting is enabled in the adobe acrobat or reader in the client machine -
Edit -> Preferences -> Internet -> Enable - Display PDF in browser.
If disabled in a client machine, the index document will open locally on the client machine and all the links in the index document might be broken as those paths might be relative from the current location(client machine).
Note - This is easy in an intranet environment, where you will have access to client machines.